| 10/08 19:00 | OH Leuven | 1-1 | Eupen |
| Sascha Kotysch 57' | 1-0 | ||
| 1-1 | 72' Isaac Nuhu | ||
| 15/08 16:30 | KRC Genk | 1-1 | OH Leuven |
| Junya Ito 55' | - | ||
| - | 85' Thomas Henry | ||
| 22/08 18:30 | OH Leuven | 1-3 | Charleroi |
| 0-1 | 6' Dorian Dessoleil | ||
| Xavier Mercier 34' | - | ||
| 1-2 | 49' Mamadou Fall | ||
| 1-3 | 80' Kaveh Rezaei | ||
| 29/08 18:30 | Waasland-Beveren | 1-3 | OH Leuven |
| - | 30' Xavier Mercier | ||
| Joseph Efford 51' | - | ||
| - | 58' Sascha Kotysch | ||
| - | 90' Thomas Henry | ||
| 12/09 18:30 | OH Leuven | 1-0 | Standard |
| Kamal Sowah 77' | - | ||
| 19/09 16:15 | KV Oostende | 3-1 | OH Leuven |
| Junior Fashion Sakala 26' | - | ||
| Junior Fashion Sakala 50' | - | ||
| Makhtar Gueye 60' | - | ||
| - | 79' Mathieu Maertens | ||
| 26/09 20:45 | KAA Gent | 2-3 | OH Leuven |
| - | 41' Kamal Sowah | ||
| - | 44' Mathieu Maertens | ||
| - | 48' Kamal Sowah | ||
| Niklas Dorsch (pen) 71' | - | ||
| Tim Kleindienst (pen) 74' | - | ||
| 03/10 18:30 | OH Leuven | 2-1 | Zulte Waregem |
| Thomas Henry 19' | - | ||
| Kamal Sowah 63' | - | ||
| - | 70' Saido Berahino | ||
| 11/10 16:00 | Knokke | 0-2 | OH Leuven |
| 18/10 20:30 | Anderlecht | 2-2 | OH Leuven |
| Yari Verschaeren 38' | - | ||
| Percy Tau 45' | - | ||
| - | 53' Frédéric Duplus | ||
| - | 84' Mathieu Maertens | ||
| 24/10 20:45 | OH Leuven | 2-1 | Club Brugge |
| Thomas Henry (pen) 21' | - | ||
| - | 45' Noa Lang (pen) | ||
| Xavier Mercier 57' | - | ||
| 31/10 16:15 | Beerschot | 4-2 | OH Leuven |
| - | 16' Xavier Mercier | ||
| Tarik Tissoudali 21' | - | ||
| Musashi Suzuki 25' | - | ||
| Ryan Sanusi 62' | - | ||
| Raphael Holzhauser 65' | - | ||
| - | 82' Thomas Henry (pen) | ||
| 23/11 20:45 | OH Leuven | 2-2 | STVV |
| - | 27' Duckens Nazon | ||
| Thomas Henry (pen) 45' | - | ||
| Josh Eppiah 73' | - | ||
| - | 84' Duckens Nazon | ||
| 30/11 20:45 | Antwerp | 3-2 | OH Leuven |
| Dylan Batubinsika 5' | - | ||
| Dieumerci Mbokani 8' | - | ||
| - | 12' Thomas Henry (pen) | ||
| - | 17' Kamal Sowah | ||
| Martin Hongla 57' | - | ||
| 05/12 18:30 | OH Leuven | 2-1 | Cercle Brugge |
| Kamal Sowah 10' | - | ||
| Thomas Henry 54' | - | ||
| - | 90' Ike Ugbo | ||
| 08/12 17:00 | OH Leuven | 2-0 | Moeskroen |
| Pierre-Yves Ngawa 56' | - | ||
| Thomas Henry 84' | - | ||
| 12/12 18:30 | KV Kortrijk | 0-3 | OH Leuven |
| 15/12 18:45 | Moeskroen | 2-2 | OH Leuven |
| - | 42' Thibault Vlietinck | ||
| - | 55' David Hubert (pen) | ||
| Joia Nuno Da Costa 71' | - | ||
| Joia Nuno Da Costa 77' | - | ||
| 20/12 16:00 | OH Leuven | 1-2 | KV Mechelen |
| - | 27' Kerim Mrabti | ||
| - | 31' David Hubert | ||
| Thomas Henry 61' | - | ||
| 26/12 18:30 | OH Leuven | 1-2 | KV Oostende |
| Kristiyan Malinov 35' | - | ||
| - | 59' Arthur Theate | ||
| - | 72' Pierre-Yves Ngawa | ||
| 10/01 18:15 | OH Leuven | ...-... | Anderlecht |
| 17/01 20:45 | STVV | ...-... | OH Leuven |
| 21/01 18:45 | Zulte Waregem | ...-... | OH Leuven |
| 24/01 20:45 | OH Leuven | ...-... | KAA Gent |
| 27/01 21:00 | Charleroi | ...-... | OH Leuven |
| 30/01 18:30 | OH Leuven | ...-... | Beerschot |
| 07/02 23:00 | Standard | ...-... | OH Leuven |
| 14/02 23:00 | OH Leuven | ...-... | KV Kortrijk |
| 21/02 23:00 | Club Brugge | ...-... | OH Leuven |
| 28/02 23:00 | OH Leuven | ...-... | Antwerp |
| 07/03 23:00 | Eupen | ...-... | OH Leuven |
| 21/03 23:00 | KV Mechelen | ...-... | OH Leuven |
| 04/04 23:00 | OH Leuven | ...-... | KRC Genk |
| 10/04 20:00? | Cercle Brugge | ...-... | OH Leuven |
| 18/04 23:00 | OH Leuven | ...-... | Waasland-Beveren |
